Table 1 Per-residue predictions: secondary structure and disorder

CASP12

NetSurfP-2.0 (hhblits)^a,b

82.4

71.1

0.604

0.011

NetSurfP-1.0^a,b

70.9

–

–

–

Spider3^a,b

79.1

–

0.582

0.026

RaptorX^a,b

78.6

66.1

0.621

0.045

Jpred4^a,b

76.0

–

–

–

DeepSeqVec

73.1 ± 1.3

61.2 ± 1.6

0.575 ± 0.075

0.026 ± 0.008

DeepProf^b

76.4 ± 2.0

62.7 ± 2.2

0.506 ± 0.057

0.022 ± 0.009

DeepProf + SeqVec^b

76.5 ± 1.5

64.1 ± 1.5

0.556 ± 0.080

0.022 ± 0.008

DeepProtVec

62.8 ± 1.7

50.5 ± 2.4

0.505 ± 0.064

0.016 ± 0.006

DeepOneHot

67.1 ± 1.6

54.2 ± 2.1

0.461 ± 0.064

0.012 ± 0.005

DeepBLOSUM65

67.0 ± 1.6

54.5 ± 2.0

0.465 ± 0.065

0.012 ± 0.005

TS115

NetSurfP-2.0 (hhblits)^a,b

85.3

74.4

0.663

0.006

NetSurfP-1.0^a,b

77.9

–

–

–

Spider3^a,b

83.9

–

0.575

0.008

RaptorX^a,b

82.2

71.6

0.567

0.027

Jpred4^a,b

76.7

–

–

–

DeepSeqVec

79.1 ± 0.8

67.6 ± 1.0

0.591 ± 0.028

0.012 ± 0.001

DeepProf^b

81.1 ± 0.6

68.3 ± 0.9

0.516 ± 0.028

0.012 ± 0.002

DeepProf + SeqVec^b

82.4 ± 0.7

70.3 ± 1.0

0.585 ± 0.029

0.013 ± 0.003

DeepProtVec

66.0 ± 1.0

54.4 ± 1.3

0.470 ± 0.028

0.011 ± 0.002

DeepOneHot

70.1 ± 0.8

58.5 ± 1.1

0.476 ± 0.028

0.008 ± 0.001

Deep BLOSUM65

70.3 ± 0.8

58.1 ± 1.1

0.488 ± 0.029

0.007 ± 0.001

CB513

NetSurfP-2.0 (hhblits)^a,b

85.3

72.0

–

–

NetSurfP-1.0^a,b

78.8

–

–

–

Spider3^a,b

84.5

–

–

–

RaptorX^a,b

82.7

70.6

–

–

Jpred4^a,b

77.9

–

–

–

DeepSeqVec

76.9 ± 0.5

62.5 ± 0.6

–

–

DeepProf^b

80.2 ± 0.4

64.9 ± 0.5

–

–

DeepProf + SeqVec^b

80.7 ± 0.5

66.0 ± 0.5

–

–

DeepProtVec

63.5 ± 0.4

48.9 ± 0.5

–

–

DeepOneHot

67.5 ± 0.4

52.9 ± 0.5

–

–

DeepBLOSUM65

67.4 ± 0.4

53.0 ± 0.5

–

–