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Table 2 Runtimes of deltaRpkm pipeline, versus two most similar tools. Since deltaRpkm does not require any assembly and annotation steps, it is difficult to compare it with other methods

From: deltaRpkm: an R package for a rapid detection of differential gene presence between related bacterial genomes

Method

Small dataset

Large dataset

deltaRpkm

N = 31, runtime = ~ 40 s

(L.monocytogenes, ~ 3 Mb)

N = 225, runtime = ~ 20 min

(L.monocytogenes)

Roary [6]

N = 24, runtime = ~ 6 min

(S.enterica, ~ 4.8 Mb) [6]

N = 1000, runtime = ~ 250 min

(S.enterica serovar Typhi) [6]

BPGA [7]

N = 28, runtime = ~ 3 min

(S.pyogenes, ~ 1.8 Mb) [7]

N = 1000, runtime = ~ 420 min

(S.pyogenes) [7]