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Table 2 Performance of six pairwise structure alignment tools on benchmarks MALIDUP and MALISAM

From: MADOKA: an ultra-fast approach for large-scale protein structure similarity searching

Benchmark

Method

Nali

RMSD

TM-score

Total Time (s)

MALIDUP

DeepAlign

85.5

2.61

0.622

10.2

 

DALI

83.5

2.65

0.600

115.3

 

MATT

82.3

2.47

0.608

63.0

 

Formatt

70.6

2.19

0.542

85.1

 

TM-align

87.0

2.62

0.631

6.4

 

MADOKA

91.7

3.43

0.631

1.2

MALISAM

DeepAlign

61.3

2.96

0.521

4.3

 

DALI

61.0

3.11

0.515

47.4

 

MATT

56.2

2.74

0.486

16.2

 

Formatt

44.9

2.42

0.411

33.1

 

TM-align

61.1

3.06

0.517

2.9

 

MADOKA

62.8

2.72

0.555

0.7

  1. *These are detailed in [33]