Fig. 4
From: DeepShape: estimating isoform-level ribosome abundance and distribution with Ribo-seq data
Improvement after introducing shape model to DeepShape. a Changing of ribosome profile shape PCC along the iteration of DeepShape-prime and DeepShape. The best performances are provided as dash dot lines (red: DeepShape, green: DeepShape-prime, yellow: STAR-uniform, purple: Ribomap). b An example of ribosome profiling improvement by DeepShape (red line) compared to DeepShape-prime (blue line). Ground-truth is shown as light green bars. The RPLP1 gene has three isoforms, including four exons (red, blue, green and yellow lines below the profile). DeepShape tends to provide the same profile in the same exons. c Distributions of isoform PCCs between calculated ribosome distributions and ground-truth