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Table 4 The genetic heterogeneity test and meta-analysis of rs744373 polymorphism using the additive model, dominant model and recessive model in East Asian and Caucasian populations

From: BIN1 rs744373 variant shows different association with Alzheimer’s disease in Caucasian and Asian populations

Comparisons

East Asian

Caucasian

East Asian VS Caucasian

 

I2

OR

95% CI

P for meta

I2

OR

95% CI

P for meta

I2

OR

95% CI

P for meta

C VS T

0.665

1.03

0.92–1.16

0.611

0.402

1.17

1.12–1.22

1.35E-12

0.541

1.12

1.06–1.19

0.000179

CC + CT VS TT

0.5

1.06

0.93–1.21

0.391

0.149

1.2

1.14–1.27

5.99E-11

0.33

1.17

1.12–1.23

3.95E-11

CC VS CT + TT

0.665

1.03

0.81–1.31

0.806

0.356

1.26

1.14–1.39

0.00001

0.499

1.19

1.10–1.29

1.35E-05