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Fig. 3 | BMC Bioinformatics

Fig. 3

From: Gencore: an efficient tool to generate consensus reads for error suppressing and duplicate removing of NGS data

Fig. 3

Comparison of speed, memory peak and processing results of different tools in both UMI and non-UMI modes. a memory peak and execution time of different tools. Samtools and Picard (in UMI mode) need to prepare the data before performing deduplication, whereas gencore and UMI_tools needn’t. b average depth of output BAM. For the cfDNA samples (1801, 1802 and 1803), the depths of UMI mode results are much higher than non-UMI mode, indicating that over-deduplication may happen when performing deduplication without UMI for ultra-deep sequencing data. c specificity of downstream variant calling results comparing to the golden standard results provided by NCCL

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BMC Bioinformatics

ISSN: 1471-2105

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