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Table 1 The weights of the epigenomic, transcriptomic and proteomic variables extracted by msPLS from the Marfan data

From: Multiset sparse partial least squares path modeling for high dimensional omics data analysis

Methylation markers Gene expression markers Cytokine markers
Site w Gene code w Marker code w
cg02394578 0.93 AKAP4 0.65 b NGF 46 0.43
cg20332866 0.96 ANXA2P3 0.63 CTACK 72 0.34
cg00906428 0.91 ASMT_A 0.83 GRO a 61 0.31
cg05024291 0.93 ATHL1 0.73 HGF 62 0.21
cg05093318 0.95 B9D2 0.66 Hu Eotaxin 43 -0.34
cg18850112 0.97 C15orf52 0.76 Hu FGF basic 44 0.46
cg07475117 0.95 C17orf54 0.44 Hu G CSF 57 0.61
cg07588614 0.94 C1orf170 0.8 Hu GM CSF 34 0.43
cg10372701 0.94 C9orf98 0.4 Hu IFN g 21 0.28
cg01718788 -0.9 CALHM1 0.84 Hu IL 10. 56 0.82
cg17061156 0.87 CHTF18 0.81 Hu IL 12 p70. 75 0.51
cg24000259 0.95 CLEC4C 0.39 Hu IL 13 51 0.44
cg25914270 0.92 COL4A6 0.69 Hu IL 15 73 0.19
cg14203970 0.91 CXorf50B 0.84 Hu IL 17 76 0.65
cg22859054 0.94 CYP1A2 0.64 Hu IL 1b 39 0.48
cg02927485 0.96 DKFZp779 0.85 Hu IL 1ra 25 0.58
cg22389215 0.88 FKRP 0.85 Hu IL 2 38 0.49
cg09570676 0.96 FUZ 0.71 Hu IL 4 52 0.26
cg14751679 0.93 GTF2IRD1 0.29 Hu IL 5 33 0.29
cg24477102 0.94 HIGD1B 0.53 Hu IL 6 19 0.04
cg24882220 0.93 ICAM5 0.85 Hu IL 7 74 0.44
cg25626012 0.95 JPH3 0.88 Hu IL 8 54 -0.26
cg26502549 0.94 LBP 0.53 Hu IL 9 77 0.42
cg00015699 0.93 LOC64322 -0.44 Hu IP 10. 48 0.72
cg01281611 0.93 LRRC50 0.66 Hu MCP 1 -0.04
cg07685390 0.95 MGC4294 0.73 Hu MIP 1a 55 0.23
cg26550872 0.97 MT1DP 0.43 Hu MIP 1b 18 0.47
cg09236780 0.92 MT1L 0.51 Hu PDGF bb 47 -0.29
cg20618527 0.92 NDUFAF2 -0.47 Hu RANTES 37 0.52
cg01546046 0.89 OR11A1 -0.53 Hu VEGF 45 0.59
cg20999565 0.96 PEX11G 0.77 IFN a2 20 0.15
cg11152012 0.87 PIF1 0.88 Il 12 p40 28 0.52
cg22958262 0.96 PIN4 0.65 Il 16 27 0.38
cg26820811 0.9 POTEF -0.72 Il 18 42 0.64
cg06731730 0.95 PRIC285 0.83 Il 1a 63 0.14
cg08531998 0.94 PSPN 0.63 Il 2Ra 13 0.56
cg19696891 0.92 PTGR1 -0.65 Il 3 64 0.24
cg27495444 0.93 REC8 0.72 LIF 29 0.57
cg17840843 0.93 RINL 0.85 M CSF 67 0.4
cg05062854 0.95 ROM1 0.69 MCP 3 26 0.42
   SLC16A3 0.78 MIF 35 0.27
   SLPI -0.63 MIG 14 0.63
   SNORA39 0.81 SCF 65 0.23
   SPATA2L 0.57 SCGF b 78 0.42
   TMEM179 0.79 SDF 1a 22 0.24
   TNFRSF6B 0.79 TNF b 30 0.26
   TRBV12_3 0.46 TRAIL 66 -0.2
   UBQLNL 0.65   
   UNQ6494 0.55   
   ZNF215 -0.76   
   ZNF574 0.74   
   ZNF688 0.65