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Table 4 The percentage variation in the chronic lymphocytic leukemia (CLL) data sources explained by the subsequent LVs of msPLS and MOFA

From: Multiset sparse partial least squares path modeling for high dimensional omics data analysis

 

Genomic variables

Epigenomic variables

Transcriptomic variables

Drug response variables

 

msPLS

MOFA

msPLS

MOFA

msPLS

MOFA

msPLS

MOFA

LV 1

72%

15%

92%

17%

92%

7.5%

57%

15%

LV 2

18%

8.2%

4%

0.5%

5%

4.7%

21%

3.5%

LV 3

2%

<0.1%

1%

<0.1%

1%

1.4%

7%

11.2%

LV 4

 

<0.1%

 

<0.1%

 

9%

 

<0.1%

LV 5

 

<0.1%

 

<0.1%

 

2.8%

 

6.1%

LV 6

 

<0.1%

 

<0.1%

 

4.8%

 

3.4%

LV 7

 

0.9%

 

2.4%

 

1.9%

 

1%

LV 8

 

<0.1%

 

0.5%

 

3.8%

 

0.5%

LV 9

 

<0.1%

 

2.6%

 

0.9%

 

0.4%

LV 10

 

<0.1%

 

<0.1%

 

2.2%

 

<0.1%

Total

92%

24%

97%

24%

98%

38%

85%

41%