Table 4 The percentage variation in the chronic lymphocytic leukemia (CLL) data sources explained by the subsequent LVs of msPLS and MOFA
From: Multiset sparse partial least squares path modeling for high dimensional omics data analysis
| Genomic variables | Epigenomic variables | Transcriptomic variables | Drug response variables | |||||
|---|---|---|---|---|---|---|---|---|
| msPLS | MOFA | msPLS | MOFA | msPLS | MOFA | msPLS | MOFA | |
| LV 1 | 72% | 15% | 92% | 17% | 92% | 7.5% | 57% | 15% |
| LV 2 | 18% | 8.2% | 4% | 0.5% | 5% | 4.7% | 21% | 3.5% |
| LV 3 | 2% | <0.1% | 1% | <0.1% | 1% | 1.4% | 7% | 11.2% |
| LV 4 | <0.1% | <0.1% | 9% | <0.1% | ||||
| LV 5 | <0.1% | <0.1% | 2.8% | 6.1% | ||||
| LV 6 | <0.1% | <0.1% | 4.8% | 3.4% | ||||
| LV 7 | 0.9% | 2.4% | 1.9% | 1% | ||||
| LV 8 | <0.1% | 0.5% | 3.8% | 0.5% | ||||
| LV 9 | <0.1% | 2.6% | 0.9% | 0.4% | ||||
| LV 10 | <0.1% | <0.1% | 2.2% | <0.1% | ||||
| Total | 92% | 24% | 97% | 24% | 98% | 38% | 85% | 41% |