Table 5 The weights of the genomic, epigenomic, and transcriptomic variables extracted by msPLS from CLL data sources
From: Multiset sparse partial least squares path modeling for high dimensional omics data analysis
Genomic variables | Epigenomic variables | Transcriptomic variables | |||
|---|---|---|---|---|---|
Name | w | Site | w | Gene code | w |
del11q22.3 | 0.31 | cg06369076 | 0.036 | ADAM29 | 0.046 |
del17p13 | 0.16 | cg22449085 | 0.036 | AGPAT4 | 0.043 |
BRAF | 0.17 | cg12208353 | 0.036 | ANK2 | 0.047 |
TP53 | 0.21 | cg04694619 | 0.037 | CRY1 | 0.049 |
IGHV | -0.66 | cg20782816 | 0.038 | DNAH3 | 0.046 |
| Â | Â | cg00832703 | 0.037 | ENO4 | -0.041 |
| Â | Â | cg01399475 | -0.036 | ESPNL | 0.043 |
| Â | Â | cg21398469 | 0.037 | GFI1 | 0.045 |
| Â | Â | cg11181763 | 0.036 | GLDN | 0.044 |
| Â | Â | cg01360627 | 0.036 | ITPRIPL2 | 0.040 |
| Â | Â | cg09087901 | 0.036 | KANK2 | 0.047 |
| Â | Â | cg04848693 | 0.037 | L3MBTL4 | 0.049 |
| Â | Â | cg12522599 | 0.038 | LDOC1 | 0.041 |
| Â | Â | cg11090458 | 0.037 | LPL | 0.041 |
| Â | Â | cg00148025 | 0.038 | MAPK4 | -0.040 |
| Â | Â | cg12032915 | 0.036 | MRO | 0.043 |
| Â | Â | cg07629149 | 0.039 | MSI2 | 0.046 |
| Â | Â | cg23844018 | 0.037 | NDUFA4L2 | 0.042 |
| Â | Â | cg05213414 | 0.037 | NUGGC | 0.041 |
| Â | Â | cg01928411 | 0.037 | PLD1 | 0.043 |
| Â | Â | cg07699978 | 0.036 | PON1 | 0.042 |
| Â | Â | cg03035162 | 0.036 | PRR18 | -0.044 |
| Â | Â | cg03462096 | 0.039 | SEPT10 | -0.040 |
| Â | Â | cg08171667 | 0.036 | SOWAHC | 0.041 |
| Â | Â | cg26441291 | 0.038 | TP63 | 0.043 |
| Â | Â | cg21400896 | 0.037 | USP6NL | -0.040 |
| Â | Â | cg15236196 | 0.036 | VSIG10 | 0.042 |
| Â | Â | cg21394039 | 0.038 | ZNF135 | -0.040 |
| Â | Â | cg04613057 | 0.036 | ZNF471 | -0.042 |
| Â | Â | cg08496123 | 0.036 | ZNF667 | 0.041 |