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Table 5 Performance of annotation transfer by homology

From: TooT-T: discrimination of transport proteins from non-transport proteins

 NameSensitivity (%)Specificity (%)Accuracy (%)MCC
ATH     
 TCDB_exact56.9295.1773.550.5440
 TCDB_high85.9085.5085.720.7112
 TCDB_med90.3864.1778.980.5737
  1. The table shows the performance homology annotation transfer with the training dataset using different thresholds. The best prediction power was achieved using the TCDB_high threshold. The predicted transporter from TCDB_exact was more reliable due to its high specificity. ATH= Annotation Transfer by Homology