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Table 2 TERT regulators of melanoma samples with (mut) and without (wt) TERT promoter mutation

From: Modelling TERT regulation across 19 different cancer types based on the MIPRIP 2.0 gene regulatory network approach

Regulators in mutP-value*Regulators in wtP-value**
AR3.97 E-37HMGA21.05 E-16
E2F13.00 E-29HIF.11.03 E-15
JUND2.86 E-25RUNX22.88 E-12
SMARCB11.85 E-15TAL11.54 E-09
ETS14.46 E-13ESR23.92 E-09
SIN3AK201.42 E-06AP-23.28 E-06
REST3.64 E-06MITF2.59 E-05
MAZ7.85 E-06WT12.80 E-05
E2F29.20 E-05SMAD35.76 E-05
TAF11.36 E-04TFAP2D2.78 E-04
BCL11A4.31 E-04PAX86.04 E-04
MYB4.73 E-04GRHL27.16 E-04
  TP531.21 E-03
  TCF71.68 E-03
  MZF13.44 E-03
  TFAP2C3.68 E-03
  NR2F27.96 E-03
  1. *indicates if a regulator was significantly more often selected in the samples with TERT promoter mutation compared to the wildtype
  2. **indicates if a regulator was significantly more often selected in the wildtype compared to the TERT promoter mutated samples