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Fig. 7 | BMC Bioinformatics

Fig. 7

From: Lag penalized weighted correlation for time series clustering

Fig. 7

An example of the effects of applying different lags to genes 1 and 2. The three panels show aligned expression vectors Y1 and Y2 and aligned timepoint vectors T1 and T2. The lagged timepoint vector indices involving NA values are dropped from the tables. Top: with no lags, X1=0 and X2=0, the temporal profiles of genes 1 and 2 are not aligned so the gene pair will have a low LPWC similarity score. Middle: with lags X1=−1 and X2=0, the patterns are aligned, and the LPWC similarity score will be high. Bottom: with X1=−1 and X2=1, the temporal shapes are once again not aligned, and the LPWC similarity score will be even lower than in the top row because the penalty for introducing lags is applied

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