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Fig. 1 | BMC Bioinformatics

Fig. 1

From: ZDOG: zooming in on dominating genes with mutations in cancer pathways

Fig. 1

Illustration of the dominator tree model. A toy signalling pathway example (left) containing protein components A to I and R, where R is the signal entry point, and its dominator tree (right). Because of the right feedback loop between H and F, only the protein R completely controls F and H, indicating that a mutation occurring in R may affect the functions of F and H more than a mutation in any other component in the pathway

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