Fig. 2
From: Automatic construction of metabolic models with enzyme constraints
General overview of the structure and workflow of the AutoPACMEN toolbox consisting of the model generator and model calibrator. The red arrows show the optional model calibrator workflow. The blue boxes indicate AutoPACMEN programs, the grey boxes for input and output files of AutoPACMEN, the orange boxes for external databases which are read out by the AutoPACMEN programs, and white boxes for optional datasets which can be provided by the user