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Fig. 3 | BMC Bioinformatics

Fig. 3

From: DryMass: handling and analyzing quantitative phase microscopy images of spherical, cell-sized objects

Fig. 3

Dry mass, refractive index, and radius of isolated HL60 cell nuclei during the cell cycle. (a) The box plots show the mean dry mass of the nuclei throughout the cell cycle stages and for two independent measurement runs. Whiskers indicate the standard deviation. The number of isolated nuclei analyzed is displayed in white for each box. (b,c) The contour plots show the fit parameter distribution (phase image fit based on the Rytov approximation; see main text for details) of the two measurement runs. The color code is identical to that in (a). The contour lines follow a multivariate kernel density estimate and correspond to the 95th, 75th, 50th, and 25th percentiles (from dark to bright). The crosses indicate the mean value of each distribution

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