TY - JOUR AU - Flati, Tiziano AU - Gioiosa, Silvia AU - Spallanzani, Nicola AU - Tagliaferri, Ilario AU - Diroma, Maria Angela AU - Pesole, Graziano AU - Chillemi, Giovanni AU - Picardi, Ernesto AU - Castrignanò, Tiziana PY - 2020 DA - 2020/08/25 TI - HPC-REDItools: a novel HPC-aware tool for improved large scale RNA-editing analysis JO - BMC Bioinformatics SP - 353 VL - 21 IS - 10 AB - RNA editing is a widespread co-/post-transcriptional mechanism that alters primary RNA sequences through the modification of specific nucleotides and it can increase both the transcriptome and proteome diversity. The automatic detection of RNA-editing from RNA-seq data is computational intensive and limited to small data sets, thus preventing a reliable genome-wide characterisation of such process. SN - 1471-2105 UR - https://doi.org/10.1186/s12859-020-03562-x DO - 10.1186/s12859-020-03562-x ID - Flati2020 ER -