Fig. 5
From: Implementing sequence-based antigenic distance calculation into immunological shape space model
Comparison of Human Serum Antibody Levels with Simulation Data. a Standardized simulated antibody levels 30 days post boost are represented as ridgeplots for each HA antigen. Standardized human serum antibody binding levels for two-age groups (18–32 years-old and 70+ years old) for each recombinant HA proteins are represented by dots below the ridgeplots. b Heatmap of the levels of human serum antibody binding level for each recombinant HA protein for both age-groups. Blue rectangles represent serum taken from younger individuals (18–32 years-old) and yellow rectangles represent older individuals (70+ years-old). c Relative fold change of day 30 post-vaccination serum antibody levels specific to the stalk region of the HA protein compared to simulation antibody levels to the stalk antigenic-site taken 30 days post-boost. Error bar represents standard deviation