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Fig. 9 | BMC Bioinformatics

Fig. 9

From: On the dynamical aspects of local translation at the activated synapse

Fig. 9

Dynamic regimes of system (1) at maximum rate of FMRP-dependent synthesis of receptor proteins and their incorporation into the membrane (kx = 40) depending on the efficiency of translation initiation (Ka), complexity of the mTOR pathway (hb) and contribution of recycling to the formation of the pool of active receptors (krz). Bifurcation diagram constructed at the intersection of the trajectory (х(t), y(t)) with the Poincaré map х(t) = 2 in the phase space (x,y,z). Parameter values: hx = 2, kx = 40, kb = 100 (a-f), kb = 200 (g-i), hb = 5 (a-c), hb = 10 (d-f), hb = 15 (g-i), Ka = 1 (a, d, g), Ka = 2 (b, e, h), Ka = 3 (c, f, i); τа = 1, τb = 2, τr = 3, τe = 3. Values of the remaining parameters are shown in the basic set (2); (b, c) periodic solution exists at krz = 0, however it does not intersect with the Poincaré plane х(t) = 2. Different colors indicate different branches of the system (1) solutions

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