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Table 2 Predicting ASCVD risk with GRS (genetic risk score) and traditional risk factors

From: Sparse reduced-rank regression for integrating omics data

 

Model 1

 

Model 2

 
 

OR

p-value

CI

OR

p-value

CI

GRS

2.354

<.001

(1.466, 3.779)

2.348

<.001

(1.460, 3.776)

age

1.155

<.001

(1.065, 1.254)

1.158

<.001

(1.067, 1.256)

sex (M vs F)

   

0.771

0.6954

(0.242, 2.459)

AUC

0.8428 vs 0.743 (Ref)

 

0.8441 vs 0.743 (Ref)

 
  1. Ref represents reference ROC; model with no risk score
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BMC Bioinformatics

ISSN: 1471-2105

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