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Fig. 2 | BMC Bioinformatics

Fig. 2

From: Accounting for grouped predictor variables or pathways in high-dimensional penalized Cox regression models

Fig. 2

Simulation results at the biomarker level. Boxplots of the number of selected biomarkers according to the different scenarios, the box bounds the interquartile range (IQR) and contains a horizontal line corresponding to the median; outside of the box, the Tukey-style whiskers extend to a maximum of 1.5*IQR beyond the box. The black diamonds are the average number of selected biomarkers. The black dashed lines indicate the true number of active biomarkers in each scenario for the simulations (a) with n=500 patients, p=1000 biomarkers and R=20 biomarker groups of equal size. Abbreviations: l, number of active groups; q, number of active biomarkers; AC: Average Coefficients; SW: Single Wald; ASW: Average Single Wald; ASW*SW: Average Single Wald product Single Wald; MSW: Max Single Wald; MSW*SW: Max Single Wald product Single Wald

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