Table 11 True positives yielded by each tool for different parameter values and the synthetic dataset
From: HPG-DHunter: an ultrafast, friendly tool for DMR detection and visualization
BSmooth | DSSSingle | methylKit | HPG-DHunter | ||||
|---|---|---|---|---|---|---|---|
Cutoff | DMRs | Thres | DMRs | Diff | DMRs | Thres | DMRs |
4 | 0 | 1e-5 | 4 | 25 | 3212 | 0..2 | 146 |
3 | 0 | 0.01 | 564 | 20 | 3608 | 0.15 | 427 |
2 | 0 | 0.05 | 1544 | 15 | 3620 | 0.1 | 2369 |
1 | 61 | 0.1 | 1950 | 10 | 3620 | 0.06 | 3681 |
0.75 | 1465 | 0.5 | 3212 | 5 | 3620 | 0.05 | 3794 |
0.5 | 3396 | 0.75 | 3651 | 3 | 3620 | 0.04 | 3856 |
0.25 | 4128 | 1 | 4098 | ||||
0.1 | 4383 | ||||||