Table 1 Homologous pairs in both training and test dataset with the sequence identity and the recognition sites
From: iPNHOT: a knowledge-based approach for identifying protein-nucleic acid interaction hot spots
Protein1(dataset)a | Protein2(dataset) | Sequence identity(%) b | Recognition site1c | Recognition site2c |
|---|---|---|---|---|
4GZNC (train) | 1AAYA (train) | 33 | E182 | R118,D120,E121,R124 |
4GZNC (train) | 4M9EA (train) | 34 | E182 | E446 |
4GZNC (train) | 5VMVA (test) | 27 | E182 | E535 |
5EXHC (train) | 3QMGA (train) | 34 | T80,H81,Q82,K88 | Q201,R213,Y216 |
4ALPA (train) | 5UDZA (train) | 74 | F77 | Y140,H148,H162 |
5EIMA (train) | 5DNOA (train) | 100 | R349,K436,T437,N477 | N336,R338 |
5DFFA (train) | 4B5FA (train) | 35 | R181 | N207,R208 |
4RCJA (train) | 4R3IA (train) | 29 | Y397 | R475 |
3WPCA (train) | 5ZLNA(test) | 72 | W47,F108,W96 | F375,F402,Y537 |
5GXHA (train) | 5H1KA (train) | 99 | F381,E197,Y474 | N13,W14,Y15,R33,M357,R359 |
5U2RA (train) | 2BPFA (train) | 96 | R283 | K280,N294 |
5U2RA | 5U8GA (train) | 100 | R283 | M236 |
5U2RA | 1BPXA (test) | 100 | R283 | R283 |
5U2RA | 4X5VA (train) | 35 | R283 | N513 |
5U2RA | 5TWPA (train) | 26 | R283 | W434, H329 |
5U2RA | 4XQ8B (train) | 34 | R283 | Y505 |
5U2RA | 5IIIA (train) | 34 | R283 | E529 |
5HO4A (test) | 2ERRA (train) | 28 | Q19,F66,E92,D49,F24,H108 | H120,F160,F158,F126 |
5HO4A | 2KXNB (test) | 28 | Q19,F66,E92,D49,F24,H108 | I195,T196,P199,S194,R111 |
5HO4A | 4CIOA | 32 | Q19,F66,E92,D49,F24,H108 | N106,Y44,N108 |
4L5RC (train) | 3RN2A (train) | 40 | N236 | K160,R244,K335,R311,K251,K198,K309,K204 |
4HN5A (train) | 1HCQA (test) | 45 | K442 | S15,H18,Y19,E25,K32 |
4HT8A (train) | 3QSUA (train) | 31 | Y25 | K33 |
4HT8A (train) | 4QVCD (train) | 100 | Y25 | N48,N28,K31 |
3SPDA (train) | 3SZQA (train) | 98 | H138,S142 | F65 |
3OSGA (train) | 1MSEC (train) | 39 | K49,R84,N139,K138,R87,F52,K51 | S187 |
3EQTA (test) | 5JBJA (train) | 43 | E573 | H406 |
1QRVA (train) | 1J5NA (train) | 38 | V32,L97 | K53,Y81,N33,R23,R36,Y28,K67,R40,Y88,K60,M29,F48,K78,K22,K85 |
3OD8A (train) | 3ODCA (train) | 32 | F44,V48 | R122,L151,R138,I154 |
5FD3A (train) | 4RKGA (train) | 31 | Y610,Y536 | R526,R543 |
2I05A (train) | 1ECRA (train) | 100 | R198 | Q250,K89 |
2I05A (train) | 4XR0A (train) | 100 | R198 | H144 |