Table 5 The synthetic repurposing of drugs for the HT
HT drug | The selected drugs by the algorithms | ||||
|---|---|---|---|---|---|
Trader | WCC | CUK | FOA | DSOS | |
Trandolapril | Cilazapril | Enalapril | Fosinopril | Fosinopril | Quinapril |
Atenolol | Esmolol | Esmolol | Alprenolol | Nebivolol | Practolol |
Carteolol | (Xamoterol+Nebivolol) | (Xamoterol+Nebivolol) | Penbutolol | Penbutolol | Penbutolol |
Nicardipine | (Cyclandelate+Nisoldipine), (Drotaverine+Nisoldipine) | (Drotaverine+Nisoldipine) | – | – | (Drotaverine+Nisoldipine) |
Felodipine | (Pinaverium+ Nisoldipine) | (Pinaverium+Nilvadipine) | (Pinaverium+Mibefradil) | (Pinaverium+Nifedipine) | (Pinaverium+Nilvadipine) |
Nifedipine | (Pinaverium + Nisoldipine) | – | – | – | – |
Nisoldipine | (Pinaverium+Isradipine), (Pinaverium+Drotaverine+Nilvadipine) | – | – | – | – |
Doxazosin | (Nicergoline) | (Droperidol) | – | – | (Dapiprazole) |
Prazosin | (Dapiprazole), (Nicergoline+Tamsulosin), (Nicergoline+Periciazine+Dapiprazole) | (Alfuzosin+Flupentixol) | (Alfuzosin+Flupentixol) | (Alfuzosin+Phentolamine) | (Alfuzosin+Silodosin) |