Table 1 Parameters variability range used during sensitivity and calibration analysis. In details, in the first column are listed the parameter names, then in the second and fourth columns the variability ranges used for the sensitivity and calibration analyses, respectively. The third column reports the initial parameters configuration. Finally, the fifth column is the optimal configuration discovered in the calibration analysis such that the quadratic error w.r.t. the real data is minimized

prob_boost

[0,0.010]

0.0025

[0.0,0.0025]

0.002474758

prob_infectionS

[0,0.005]

0.0031

[0.0025,0.0100]

0.002537443

prob_infectionR_l1

[0,0.010]

0.0023

[0.0,0.0025]

0.002458887

init_S_a1

[0,866703]

866703

[0,866703]

866696

init_S_a2

[0,15685693

15685693

[0,15685693

15685680

init_S_a3

[0,37837299]

37837299

[0,37837299]

37628100

init_R_a1_nv_l4

[0,866703]

0

[0,866703]

7

init_R_a2_nv_l1

[0,15685693]

0

[0,15685693]

4

init_R_a2_nv_l2

[0,15685693]

0

[0,15685693]

2

init_R_a2_nv_l3

[0,15685693]

0

[0,15685693]

2

init_R_a2_nv_l4

[0,15685693]

0

[0,15685693]

2

init_R_a3_nv_l1

[0,37837299]

0

[0,37837299]

209184

init_R_a3_nv_l2

[0,37837299]

0

[0,37837299]

4

init_R_a3_nv_l3

[0,37837299]

0

[0,37837299]

4

init_R_a3_nv_l4

[0,37837299]

0

[0,37837299]

4