FluConvert and IniFlu: a suite of integrated software to identify novel signatures of emerging influenza viruses with increasing risk

Table 1 The 247 residues differentially occurring between RRKR and RETR consensus signatures are polygenic

	Influenza viral proteins
	PB2	PB1	PA	HA	NP	NA	M1	M2	NS1	NS2	PB1-F2
Segment size^a	763	757	729	569	499	475	271	99	230	121	90
No. of consensus signatures between groups^b(%)	20 (2.62)	1 (0.13)	23 (3.16)	77 (13.53)	1 (0.2)	18 (3.79)	15 (5.54)	8 (8.08)	69 (30)	7 (5.79)	8 (8.89)

^a: The H5N2 viral genome is composed of 4603 amino acid residues divided into 11 viral proteins. The size of each segment is indicated by the number of residues as shown
^b: Unique amino acid residues are identified by comparing the consensus sequences between the two studied subgroups. Numbers shown are the counts of the characteristic residues in each viral protein. The variations in each viral protein are expressed by the percentage of unique residues indicated in the parentheses

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