Skip to main content
Fig. 4 | BMC Bioinformatics

Fig. 4

From: SpectralTAD: an R package for defining a hierarchy of topologically associated domains using spectral clustering

Fig. 4

The effect of the hierarchy of TAD boundaries detected by SpectralTAD on the average number of annotations in enriched (a) & depleted (b) genomic markers and on enrichment (c) and depletion (d) for different genomic annotations. Results for Level 1, 2, and 3 boundaries are shown. Genomic annotations were considered within 50 kb regions flanking a boundary on both sides. Wilcoxon test p-values are shown in panel a & b, and aggregated p-values, using the Fisher’s method, are shown for panels c & d. Raw data from the GM12878 cell line, chromosome 1–22, 25 kb resolution

Back to article page

BMC Bioinformatics

ISSN: 1471-2105

Contact us