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Fig. 8 | BMC Bioinformatics

Fig. 8

From: Construction and optimization of gene expression signatures for prediction of survival in two-arm clinical trials

Fig. 8

The area between hROC curves (Abc) is used for model optimization in prediction for TNBC. The area between the hazard-ratio ROC curves (Abc) is plotted as a function of mtop, the number of genes used by feature selection in the multivariate Cox MOA model for TNBC. Representative hROC curves for specific values of mtop are shown below. The hROC curves for mtop = 35 are the most separated, corresponding to the maximum value of Abc

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