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Table 2 The expression pattern (up-regulation or down-regulation) of motif nodes in Signature and Anti-Signature

From: An integrative network-driven pipeline for systematic identification of lncRNA-associated regulatory network motifs in metastatic melanoma

Variable

Signature

Anti-Signature

Motif 1

CDK4 (UP)

CDK4 (DOWN)

SNHG5 (UP)

SNHG5 (DOWN)

hsa-let-7a-3p (DOWN)

hsa-let-7a-3p (UP)

Motif 2

GATA3 (DOWN)

GATA3 (UP)

SNHG5 (UP)

SNHG5 (DOWN)

hsa-let-7a-3p (DOWN)

hsa-let-7a-3p (UP)

Motif 3

AKT1 (UP)

AKT1 (DOWN)

UCA1 (UP)

UCA1 (DOWN)

hsa-miR-125b-1 (DOWN)

hsa-miR-125b-1 (UP)