Fig. 3
From: Drug-target interactions prediction using marginalized denoising model on heterogeneous networks
Illustration of the prediction scenarios on old drug repositioning and new drug/target discovery. There are 5 drugs (i.e., D1 - D5) and 4 targets (i.e., T1 - T4). For the D1-T1 interaction pair in a circle, D1 is a known drug, T1 is a known target, and the prediction result on D1-T1 pair is the old drug repositioning in (a); D1 is a new drug, T1 is a known target, and the prediction result on D1-T1 pair is the new drug discovery in (b); D1 is a known drug, T1 is a new target, and the prediction result on D1-T1 pair is the new target discovery in (c)