Fig. 2From: Cell cycle control and environmental response by second messengers in Caulobacter crescentusc-di-GMP regulates DNA replication and cell motility through CtrA. (Left-hand side) cdG directly stimulates phosphatase activity of CckA, thereby dephosphorylating CtrA to allow the initiation of DNA replication. (Right-hand side) cdG is also required for CtrA proteolysisBack to article page