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Table 1 Significantly mutated genes in tumor samples of 55 patients with LUAD. The genes were classified as an oncogene (OG) and a tumor suppressor gene (TSG) based on their scores and the cancer gene census information by SomInaClust R package

From: Analysis of genomic and transcriptomic variations as prognostic signature for lung adenocarcinoma

Gene

# Mutations

Q value

OG Score

TSG Score

Classification

CGCa

EGFR

11

1.57e-12

80

0

OG

Dom

KRAS

8

1.57e-12

100

0

OG

Dom

TP53

20

4.8e-07

62.5

55

TSG

Rec

STK11

7

0.000106

0

85.7

TSG

Rec

RB1

7

0.0049

0

71.4

TSG

Rec

MGA

6

0.0217

0

80

TSG

NA

  1. aCancer gene census (Dom Dominant, Rec Recessive)