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Table 7 Gene Ontology(GO) analysis of different feature types. The entries for Gene, CEEdge and PPIEdge indicate the Benjamini corrected p-value for that GO term

From: Robust edge-based biomarker discovery improves prediction of breast cancer metastasis

GO term Gene CEEdge PPIEdge
Cell cycle 2.3E-15 4.5E-19 2.0E-30
Sister chromatid cohesion 4.4E-5 1.7E-5 5.1E-12
Anaphase-promoting complex-dependent catabolic process 4.4E-5 8.8E-6 1.4E-7
Negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 3.9E-4 3.2E-4 1.1E-5
Antigen processing and presentation of exogenous peptide antigen via MHC class II 7.1E-4 3.8E-2 2.9E-3
DNA repair 4.2E-1 3.8E-1 8.8E-3
Positive regulation of telomere maintenance via telomerase 3.6E-1   1.4E-2
Cell-cell adhesion    1.7E-2
T cell receptor signaling pathway 6.0E-1 9.7E-1 6.7E-2
p53 signaling pathway 4.9E-2 1.1E-1 6.4E-2
RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage 7.6E-1 9.0E-1 1.2E-1
Wnt signaling pathway, planar cell polarity pathway 8.1E-1 5.3E-1 2.1E-1
Natural killer cell mediated cytotoxicity 9.5E-1   8.8E-1
Focal adhesion    9.7E-1
Small cell lung cancer 7.0E-1 6.3E-1 3.8E-2
Jak-STAT signaling pathway 9.7E-1 9.9E-1 9.5E-1
Tumor necrosis factor-mediated signaling pathway 6.5E-1 5.9E-1 2.1E-2