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Table 7 Gene Ontology(GO) analysis of different feature types. The entries for Gene, CEEdge and PPIEdge indicate the Benjamini corrected p-value for that GO term

From: Robust edge-based biomarker discovery improves prediction of breast cancer metastasis

GO term

Gene

CEEdge

PPIEdge

Cell cycle

2.3E-15

4.5E-19

2.0E-30

Sister chromatid cohesion

4.4E-5

1.7E-5

5.1E-12

Anaphase-promoting complex-dependent catabolic process

4.4E-5

8.8E-6

1.4E-7

Negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle

3.9E-4

3.2E-4

1.1E-5

Antigen processing and presentation of exogenous peptide antigen via MHC class II

7.1E-4

3.8E-2

2.9E-3

DNA repair

4.2E-1

3.8E-1

8.8E-3

Positive regulation of telomere maintenance via telomerase

3.6E-1

 

1.4E-2

Cell-cell adhesion

  

1.7E-2

T cell receptor signaling pathway

6.0E-1

9.7E-1

6.7E-2

p53 signaling pathway

4.9E-2

1.1E-1

6.4E-2

RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage

7.6E-1

9.0E-1

1.2E-1

Wnt signaling pathway, planar cell polarity pathway

8.1E-1

5.3E-1

2.1E-1

Natural killer cell mediated cytotoxicity

9.5E-1

 

8.8E-1

Focal adhesion

  

9.7E-1

Small cell lung cancer

7.0E-1

6.3E-1

3.8E-2

Jak-STAT signaling pathway

9.7E-1

9.9E-1

9.5E-1

Tumor necrosis factor-mediated signaling pathway

6.5E-1

5.9E-1

2.1E-2