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Fig. 5 | BMC Bioinformatics

Fig. 5

From: ImmunoGlobe: enabling systems immunology with a manually curated intercellular immune interaction network

Fig. 5

Immune network structure can be used to examine the network effects of immune stimuli. a A network visualization of the nodes involved in the immune response to LPS. Immune cells involved are arranged in layers corresponding to their degree of connection to the stimulus, with other interacting immune components grouped together at the bottom. Direct cell:cell edges are shown in darker grey, with all other edges involved in response to LPS shown in light grey. Immune cell node size corresponds to the number of paths between the stimulus and cell, and node color corresponds to activation score of the cell. b A scatter plot showing a positive correlation between the number of shortest paths that exist between a stimulus and a cell and the activation score of that cell. Data points are colored according to immune cell type and shaped according to stimulus

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BMC Bioinformatics

ISSN: 1471-2105

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