From: Cells in Silico – introducing a high-performance framework for large-scale tissue modeling
Parameter | Description |
---|---|
V0 | Target volume |
S0 | Target surface |
λV | Volume coupling factor |
λS | Surface coupling factor |
Ai,j | Adhesion coupling matrix |
Size change | constant rate of change of V0 and S0 |
Diffusion matrix | Diffusion constant matrix |
Signal decay | Signal decay per time-step (relative and absolute) |
Constant signal | Has constant signal |
Start signal | Cells of this type are initiated with the signal content |
Division | |
Rate | Division rate |
Age | Minimum division age |
Signal thresholds | Minimum and maximum signal value |
Mutation matrix | Probability to mutate to another type |
Cell death | |
Apoptotic cell type | Cell type of the apoptotic cells |
Rate | Cell death rate |
Age | Minimum cell age |
Signal thresholds | Minimum and maximum signal value |