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Table 2 Cell type properties (set by config file)

From: Cells in Silico – introducing a high-performance framework for large-scale tissue modeling

Parameter

Description

V0

Target volume

S0

Target surface

λV

Volume coupling factor

λS

Surface coupling factor

Ai,j

Adhesion coupling matrix

Size change

constant rate of change of V0 and S0

Diffusion matrix

Diffusion constant matrix

Signal decay

Signal decay per time-step (relative and absolute)

Constant signal

Has constant signal

Start signal

Cells of this type are initiated with the signal content

Division

 

Rate

Division rate

Age

Minimum division age

Signal thresholds

Minimum and maximum signal value

Mutation matrix

Probability to mutate to another type

Cell death

 

Apoptotic cell type

Cell type of the apoptotic cells

Rate

Cell death rate

Age

Minimum cell age

Signal thresholds

Minimum and maximum signal value