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Fig. 1 | BMC Bioinformatics

Fig. 1

From: Theoretical characterisation of strand cross-correlation in ChIP-seq

Fig. 1

Illustration of the ChIP-seq read density model. The genome whose length is G contains n binding events. There is a pair of read-enriched regions which belong to Ef or Eg on both sides of each binding element. All the enriched regions have the same width w and the forward and the reverse enriched regions in a pair have a distance d, which corresponds to the minimum DNA fragment length, across a binding element. We assumed that M is the total number of (uniquely) mapped reads in a sample and the numbers of mapped reads into the forward and reverse are same. The total number of the signal reads is denoted Mα with the S/N parameter α. The total number of the noise reads can be described as M(1−α)

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