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Table 2 Edge correctness score and sequence similarity score (mean values) for 45 pairs of virus-host protein-protein interaction networks from the STRING Viruses database, for the integer linear programming formulation and different values of the λ parameter. The maximum sum of the edge correctness and sequence similarity scores is achieved at λ=0.4, followed by λ=0.5. Sequence similarity scores are normalized global alignment scores

From: Alignment of biological networks by integer linear programming: virus-host protein-protein interaction networks

λ

Edge

Sequence

 

Correctness

Similarity

0.0

0.8655

0.7444

0.1

0.8654

0.8529

0.2

0.8648

0.8622

0.3

0.8647

0.8681

0.4

0.8612

0.8731

0.5

0.8565

0.8770

0.6

0.8493

0.8801

0.7

0.8299

0.8872

0.8

0.7820

0.8960

0.9

0.6698

0.9057

1.0

0.1054

0.9144