Fig. 2

MADA web application interface and case results. a WorkFlow form, where the user uploads their custom datasets and submits the request of processing. b Densityplot shows DNA methylation levels (as β values) for pre-receptive (LH + 2) and receptive (LH+ 8) endometrium samples from 17 women. c Mdsplot drawn with the largest difference between the first 1000 samples, can be used to reflect the similarity of samples. d Boxplot shows the data of each chip is still tidy so that we can detect DMPs or DMRs in the next step. e Volcano plot shows the degree of difference in CpG sites within different methylation periods. f Scatter plot can be used to reflect the distribution of CpG sites on chromosomes. g Pie plot shows the gene region feature category (UCSC) of significant CpG sites, and the percentage of significant CpG sites in different gene annotation region directly. h More detailed numerical information can be seen in table