Table 6 Target proteins of Nefazodone
From: Literature based discovery of alternative TCM medicine for adverse reactions to depression drugs
TARGET | STMBOL | ACTIONS |
|---|---|---|
A5-hydroxytryptamine receptor 2A | HTR2A | antagonist |
A5-hydroxytryptamine receptor 2C | HTR2C | antagonist |
ASodium-dependent serotonin transporter | SERT | inhibitor |
A5-hydroxytryptamine receptor 1A | HTR1A | antagonist |
ASodium-dependent noradrenaline transporter | SERT | inhibitor |
USodium-dependent dopamine transporter | SLC6A3 | inhibitor |
UAlpha-1B adrenergic receptor | ADRA1B | other/unknown |
UAlpha-2A adrenergic receptor | ADRA2A | antagonist |
NAlpha-1A adrenergic receptor | ADRA1A | antagonist |
UPotassium voltage-gated channel subfamily H member 2 | KCNG1 | antagonist |