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Table 2 Results of overrepresentation analysis for the enriched Novel SCZ associated genes

From: Differential gene regulatory pattern in the human brain from schizophrenia using transcriptomic-causal network

Enrichment Pathway description p-value p. adjust Gene symbol
KEGG FoxO signaling pathway 0.0324 0.0445 FBXO32
KEGG Axon guidance 0.0446 0.0446 UNC5D
GO protein phosphorylated amino acid binding 0.0115 0.0319 RTF1
GO RNA polymerase II complex binding 0.0119 0.0319 RTF1
GO RNA polymerase core enzyme binding 0.0137 0.0319 RTF1
GO basal transcription machinery binding 0.0162 0.0319 RTF1
GO basal RNA polymerase II transcription machinery binding 0.0163 0.0319 RTF1
GO RNA polymerase binding 0.0171 0.0319 RTF1
GO phosphoprotein binding 0.0186 0.0319 RTF1
GO single-stranded DNA binding 0.0253 0.0380 RTF1
Reactome FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes 0.0081 0.0323 FBXO32
Reactome Netrin-1 signaling 0.0140 0.0323 UNC5D
Reactome E3 ubiquitin ligases ubiquitinate target proteins 0.0165 0.0323 RTF1
Reactome Formation of RNA Pol II elongation complex 0.0171 0.0323 RTF1
Reactome RNA Polymerase II Transcription Elongation 0.0171 0.0323 RTF1
Reactome FOXO-mediated transcription 0.0182 0.0323 FBXO32
Reactome Protein ubiquitination 0.0221 0.0323 RTF1
Reactome RNA Polymerase II Pre-transcription Events 0.0234 0.0323 RTF1
DO lateral sclerosis 0.0275 0.0813 FBXO32
DO amyotrophic lateral sclerosis 0.0383 0.0813 FBXO32
DO motor neuron disease 0.0462 0.0813 FBXO32
DO chronic obstructive pulmonary disease 0.0542 0.0813 FBXO32
DO obstructive lung disease 0.0755 0.0905 FBXO32