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Table 1 Top genes after P-value combination

From: NIMBus: a negative binomial regression based Integrative Method for mutation Burden Analysis

Rank

Gene

P value

Adjusted P value

PubMed ID

1

TP53

4.33E−139

4.3311E−139

17401424

2

DDX3X

7.30E−18

3.64888E−18

22820256

3

KRAS

7.68E−06

2.56097E−06

19847166

4

MUC4

1.79E−05

4.46636E−06

19935676

5

CDH1

1.53E−04

3.06519E−05

10973239

6

ARID1A

1.42E−03

0.000236255

22037554

7

SMARCA4

2.64E−03

0.000377726

18386774

8

FGFR1

5.94E−03

0.000742868

23817572

9

OTOP1

3.33E−02

0.003694811

10

STK11

4.69E−02

0.004691876

11

SPOP

4.94E−02

0.004493795

12

PTEN

5.77E−02

0.004812088

13

SMO

1.65E−01

0.012684045

14

TAS2R31

4.76E−01

0.033983962

15

TBC1D29

5.14E−01

0.034276895