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Table 2 Significant pathways and P values

From: NIMBus: a negative binomial regression based Integrative Method for mutation Burden Analysis

KEGG ID

Description

LICA

GACA

LUAD

BRCA

04115

p53 signaling pathway

****

****

–

****

04210

Apoptosis

****

****

–

****

04110

Cell cycle; growth and death

*

–

–

–

04919

Thyroid hormone signaling

***

****

*

**

05014

Amyotrophic lateral sclerosis

****

****

**

****

04310

Wnt signaling pathway

–

****

–

–

04722

Neurotrophin signaling

–

****

–

****

04010

MAPK signaling pathway

–

***

–

–

05216

Thyroid cancer pathway

–

*

–

–

05219

Bladder cancer, urothelial tumor

–

*

–

–

04742

Taste transduction

–

–

*

–

  1. *P ≤ 0.05, **P ≤ 0.01, ***P ≤ 0.001, ****P ≤ 0.0001