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Fig. 4 | BMC Bioinformatics

Fig. 4

From: Feature selection algorithm based on dual correlation filters for cancer-associated somatic variants

Fig. 4

3-step variant filtering procedure. Three steps of filtering for cancer-associated variants extraction are illustrated in this figure. In the first step, we identified the functional role of variant considering whether it directly affects protein synthesis. Next, we searched public databases to eliminate non-critical variants, and also referred to previous studies to include variants known to be important for the cancer. Finally, the last step confirmed that the variant did not occur accidentally during the sequencing or variant calling and was deeply related to the cancer samples

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