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Table 3 Biological significance of four omics of C3 proteins of BRCA

From: C3: connect separate connected components to form a succinct disease module

Data (#proteins) mRNA expression
(125)
#proteins (p value)
Mutation(106)
#proteins
(p value)
DNA methylation
(105)
#proteins (p value)
CNV(134)
#proteins (p value)
OMIM(7952) 100(0) 75(0.0056) 85(0) 91(0.01652)
GWAS(5022) 61(0.00371) 57(0.00022) 50(0.01305) 53(0.2789)
Drug-target(2635) 40(0.00035) 32(0.00328) 38(0.00002) 34(0.04129)
  1. PPI network: 13,460 proteins. The italics number means less than 0.05