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Table 3 Biological significance of four omics of C3 proteins of BRCA

From: C3: connect separate connected components to form a succinct disease module

Data (#proteins)

mRNA expression

(125)

#proteins (p value)

Mutation(106)

#proteins

(p value)

DNA methylation

(105)

#proteins (p value)

CNV(134)

#proteins (p value)

OMIM(7952)

100(0)

75(0.0056)

85(0)

91(0.01652)

GWAS(5022)

61(0.00371)

57(0.00022)

50(0.01305)

53(0.2789)

Drug-target(2635)

40(0.00035)

32(0.00328)

38(0.00002)

34(0.04129)

  1. PPI network: 13,460 proteins. The italics number means less than 0.05