From: Generation of digital patients for the simulation of tuberculosis with UISS-TB
Feature | Range | Units | Type | Notation |
---|---|---|---|---|
Bacterial load in sputum | [0–10000] | CFU | D | MtbSputum |
MTB virulence | [0–1] | — | C | strain |
CD4 T cell type 1 | [0–100] | \(\hbox {cells}/\upmu \hbox {L}\) | D | Th1 |
CD4 T cell type 2 | [0–100] | \(\hbox {cells}/\upmu \hbox {L}\) | D | Th2 |
Specific IgG titers | [0–512] | IgG titer | C | IGg |
CD8 T cell | [0–1134] | \(\hbox {cells}/\upmu \hbox {L}\) | D | TC |
Interleukin 1 | [0–235] | pg/mL | C | IL1 |
Interleukin 2 | [0–894] | pg/mL | C | IL2 |
Interleukin 10 | [0–516] | pg/mL | C | IL10 |
Interleukin 12 | [0–495] | pg/mL | C | IL12 |
Interleukin 17 | [0–704] | pg/mL | C | IL17 |
Interleukin 23 | [0–800] | pg/mL | C | IL23 |
Interferon-\(\alpha\) | [0–148.4] | pg/mL | C | IFN1A |
Interferon-\(\beta\) | [0–206] | pg/mL | C | IFN1B |
Interferon-\(\gamma\) | [0–268.2] | pg/mL | C | IFng |
TNF- | [0–49.4] | pg/mL | C | TFN |
LXA4 | [0–3] | ng/mL | C | LXA4 |
PGE2 | [0–2.1] | ng/mL | C | pgE2 |
Vitamin D | [25–80] | ng/mL | C | VD |
Regulatory T cells | [0–200] | \(\hbox {cells}/\upmu \hbox {L}\) | D | Treg |
Age | [10–80] | years | D | Age |
Body Mass Index | [18.5–35] | \(\hbox {kg}/\hbox {m}^{2}\) | C | BMI |