Fig. 2
From: ISSEC: inferring contacts among protein secondary structure elements using deep object detection
Paradigm of ISSEC. a Initially, an multiple sequence alignment (MSA) was built for query protein. b The inter-residue contacts were predicted through running CCMPred over the calculated MSA. c, d ISSEC takes the predicted inter-residue contact map as input and identifies the contacting SSEs (shown as red rectangle). e The true inter-SSE contacts (shown as red rectangle) annotated according to native structure of the query protein