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Fig. 3 | BMC Bioinformatics

Fig. 3

From: LAMP: disease classification derived from layered assessment on modules and pathways in the human gene network

Fig. 3

Layered networks and LAMP classification approach flow. a Illustration of layered networks of the original network with 36 nodes and 62 edges. The forward layered network is on the top with green nodes as the source nodes. The reverse layered network is on the bottom with red nodes as the target nodes. Orange nodes and dashed edges do not belong to these layered networks. b Flow diagram of the LAMP classification approach. 1726 diseases are divided into 2 group in gene screening process corresponding to whether the disease genes are all screened in DOWN_LSCC. Answer yes to get diseases group1, which are considered to belong to the same category, denoted by CATG-0. Answer no to get diseases group2. Preliminary results are obtained after hierarchical clustering. Refined results are obtained from the tSNE diagram, which together with CATG-0 constituted the final results

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