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Table 5 Comparison of different classifiers based on the cross-validation results on the training datasets for the three species

From: m5CPred-SVM: a novel method for predicting m5C sites of RNA

Species Classifiers Sn (%) Sp (%) Pre (%) Acc (%) Mcc F1score AUROC
H. Sapiens SVM 85.5 80.0 81.0 82.8 0.656 0.832 0.899
XGBoost 82.5 79.5 80.1 81.0 0.620 0.813 0.879
RF 77.5 77.0 77.1 77.3 0.550 0.773 0.849
KNN 84.5 72.5 75.5 78.5 0.574 0.797 0.850
Adaboost 79.5 73.5 75.0 76.5 0.530 0.772 0.860
DT 68.0 65.0 66.1 66.5 0.330 0.670 0.678
LR 62.0 61.5 61.7 61.8 0.235 0.618 0.617
M. musculus SVM 75.7 72.8 73.6 74.3 0.486 0.746 0.822
XGBoost 76.1 73.6 74.3 74.9 0.498 0.752 0.823
RF 75.9 71.6 72.8 73.7 0.476 0.743 0.814
KNN 67.3 67.5 67.5 67.4 0.349 0.674 0.729
Adaboost 74.2 72.6 73.0 73.4 0.468 0.736 0.812
DT 62.6 62.3 62.4 62.5 0.250 0.630 0.615
LR 73.3 73.2 73.2 73.2 0.465 0.733 0.811
A. thaliana SVM 68.1 75.5 73.5 71.8 0.437 0.707 0.782
XGBoost 65.1 76.3 73.3 70.7 0.417 0.690 0.770
RF 66.1 76.8 74.1 71.5 0.432 0.699 0.778
KNN 58.0 78.6 73.1 68.3 0.375 0.647 0.734
Adaboost 65.2 74.2 71.6 69.7 0.395 0.683 0.756
DT 59.5 60.0 59.8 59.8 0.200 0.600 0.587
LR 64.4 69.8 68.1 67.1 0.342 0.662 0.730
  1. Bold numbers indicate the highest values in each column for different species