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Table 5 Comparison of different classifiers based on the cross-validation results on the training datasets for the three species

From: m5CPred-SVM: a novel method for predicting m5C sites of RNA

Species

Classifiers

Sn (%)

Sp (%)

Pre (%)

Acc (%)

Mcc

F1score

AUROC

H. Sapiens

SVM

85.5

80.0

81.0

82.8

0.656

0.832

0.899

XGBoost

82.5

79.5

80.1

81.0

0.620

0.813

0.879

RF

77.5

77.0

77.1

77.3

0.550

0.773

0.849

KNN

84.5

72.5

75.5

78.5

0.574

0.797

0.850

Adaboost

79.5

73.5

75.0

76.5

0.530

0.772

0.860

DT

68.0

65.0

66.1

66.5

0.330

0.670

0.678

LR

62.0

61.5

61.7

61.8

0.235

0.618

0.617

M. musculus

SVM

75.7

72.8

73.6

74.3

0.486

0.746

0.822

XGBoost

76.1

73.6

74.3

74.9

0.498

0.752

0.823

RF

75.9

71.6

72.8

73.7

0.476

0.743

0.814

KNN

67.3

67.5

67.5

67.4

0.349

0.674

0.729

Adaboost

74.2

72.6

73.0

73.4

0.468

0.736

0.812

DT

62.6

62.3

62.4

62.5

0.250

0.630

0.615

LR

73.3

73.2

73.2

73.2

0.465

0.733

0.811

A. thaliana

SVM

68.1

75.5

73.5

71.8

0.437

0.707

0.782

XGBoost

65.1

76.3

73.3

70.7

0.417

0.690

0.770

RF

66.1

76.8

74.1

71.5

0.432

0.699

0.778

KNN

58.0

78.6

73.1

68.3

0.375

0.647

0.734

Adaboost

65.2

74.2

71.6

69.7

0.395

0.683

0.756

DT

59.5

60.0

59.8

59.8

0.200

0.600

0.587

LR

64.4

69.8

68.1

67.1

0.342

0.662

0.730

  1. Bold numbers indicate the highest values in each column for different species