Fig. 4
From: Inferring chromosome radial organization from Hi-C data
Paternal and maternal homologs follow a similar CT distribution pattern. a, b Pairwise inter-chromosomal strong interaction pattern matrices for GM12878 paternal (a) and maternal (b) copies. c 2D PCA projection of the pairwise inter-chromosomal strong interaction pattern matrix for GM12878 paternal copy. d, e Correlation of GM12878 paternal copy PC1 values with maternal copy (d) and diploid averaged GM12878 (e) PC1 values obtained from the PCA transformation of the respective pairwise inter-chromosomal strong interaction pattern matrices. f, g Network modeling generated model clusters for both GM12878 paternal (f) and maternal (g) copies, selected based on respective inferred CT distribution types. h Predicted radial distance distributions of 4 CTs (chr18, chr19, chr1 and chr20) for GM12878 diploid averaged, paternal and maternal copies, obtained from the respective selected model clusters (# of models in the selected clusters: GM12878 diploid average—109, paternal—194, and maternal—148)