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Table 3 Top five candidate lncRNAs highly prioritized to be associated with ASD.

From: Prediction and prioritization of autism-associated long non-coding RNAs using gene expression and sequence features

Gene ID

Gene symbol

Annotation

Co-expressed protein-coding genes in the BrainSpan dataset

(PCC>0.95)*

Traits reported in GWAS Catalog**

ENSG00000229807

XIST

X inactive specific transcript

\

\

ENSG00000240801

AC132217.1

3' overlapping ncRNA IGF2

IGF2

Birth weight

ENSG00000228971

LINC02607

Long intergenic non-protein coding RNA 2607

\

Intelligence, cognitive performance

ENSG00000258283

AC011603.4

Antisense to DDN

DDN

Intelligence, cognitive ability, Bipolar disorder

ENSG00000221857

AC020907.2

Novel transcript

GNPTG, NDRG2, TNFSF12, TNFSF12-TNFSF13

\

  1. *The protein-coding genes co-expressed with the candidate lncRNAs in the BrainSpan dataset are indicated. Pearson Correlation Coefficient (PCC) > 0.95 was used to select the co-expressed gene pairs.
  2. **Traits reported to be associated with the genomic loci from which the candidate lncRNAs are transcribed. Information was retrieved from GWAS Catalog (https://www.ebi.ac.uk/gwas/).
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BMC Bioinformatics

ISSN: 1471-2105

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