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Fig. 7 | BMC Bioinformatics

Fig. 7

From: Validation of a yellow fever vaccine model using data from primary vaccination in children and adults, re-vaccination and dose-response in adults and studies with immunocompromised individuals

Fig. 7

Fourth scenario: immune response in individuals using immunomodulatory therapy. Interquartile range (rectangles), median (black line), lower limit and upper limit (black stems) and geometric means (observed and estimated by the model) of YF antibody titers according to post-vaccination time, for control individuals and those under use of combination immunomodulatory therapy. “GMT Control Data” ( ) refers to the geometric mean of experimental data obtained from control individuals and “GMT Control Model” ( ) to the geometric mean of numerical results obtained when using the original parameters values. “GMT Immunomodulatory Data” ( ) refers to the geometric mean of experimental data obtained from individuals using the therapy and “GMT Immunomodulatory Model” ( ) to the geometric mean of the numerical results obtained when using the adjusted parameters. Experimental data expressed in reciprocal dilution, and numerical ones in PRNT mIU/mL

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